Publications

Selected documentation on HLA and non-HLA antibodies and articles related to the development of the XM-ONE^® donor-specific endothelial cell crossmatch test kit.

 XM-ONE: Publications

• Jackson, AM et al; Clinical Relevance and IgG Subclass Determination of Non-HLA Antibodies Identified Using Endothelial Cell Precursors Isolated From Donor Blood, Transplantation, April 2011 (Epub ahead of print)
• Alheim M et al.: A flow cytometric crossmatch test for simultaneous detection of antibodies against donor lymphocytes and endothelial precursor cells.Tissue Antigens 2010 Jan 12. [Epub ahead of print]
• Breimer M et al.: Multicenter Evaluation of a Novel Endothelial Cell Crossmatch Test in Kidney Transplantation. Transplantation Volume 87, Number 4, February 27, 2009, pp 549-556
• Grandtnerová B et al.: Hyperacute Rejection of Living Related Kidney Grafts Caused by Endothelial Cell-Specific Antibodies: Case Reports.Transplantation Proceedings 2008; 40: 2422-2424
• Holgersson J, Elsheikh E, Grufman P, Sumitran-Holgersson S, Tydén G: A case of vascular rejection caused by endothelial reactive non-HLA antibodies. Clinical Transplants 2006 Ed P Terasaki, 2007; 535-538

XM-ONE: Abstracts poster presentations at scientific meetings

• Sigurdardottir, V et al, The clinical relevance of autoreactiveand donor-specific anti-endothelial cell antibodies with early acute rejections in heart transplant patients

• Holgersson J et al.: A flow cytometric crossmatch test for simultaneous detection of antibodies against donor lymphocytes and endothelial cells. ATC annual meeting 2009, Poster no 1143
• Procter, J et al.: Evaluation of the XM-ONE®Assay and the Role of Endothelial Cell Antibodies in Recipients of Living Donor Renal Transplants. EFI meeting May 2009, Ulm, Poster
• Alheim M et al.: Single-tube crossmatch assay for simultaneous detection of anti-bodies reactive with donor endothelial cells and lymphocytes. EFI meeting April 2008, Poster
• Fort M et al.: A serologic kidney acute vascular rejection despite a full HLA matched living donor. EFI meeting April 2008, Poster
• Rydberg L et al.: A single center experience of the XM-One endothelial crossmatch test. EFI meeting May 2007, Poster no 211
• Jackson A et al.: A new donor-specific endothelial cell cross match predicts early rejection in renal transplants. ATC congress, May 2007, Poster no 751 

Overview publications

• Sumitran-Holgersson S and Holgersson J: Clinical importance of non-HLA antibodies in solid organ transplantation. Current Opinion in Organ Transplantation 2006; 11: 425-432
• Glotz D, Lucchiari N, Pegaz- Fiornet B, Suberbielle-Boissel C: Endothelial cells as targets of allograft rejection. Transplantation 2006; Volume 82, Number 1S: S19-21
• Terasaki P: Humoral Theory of Transplantation. American Journal of Transplantation 2003; 3: 665-673

Publications on the importance of endothelial cell antibodies

• Smith J et al.: A Reevaluation of the Role of IgM Non-HLA Antibodies in Cardiac Transplantation. Transplantation 2009; 87: 864-871
• Tydén G, Sandberg J, Elinder C-G, Berg U: Successful Transplantation of two children with antiendothelial cell antibodies. Transplantation Proceedings 2003; 35: 792-793
• Vermehren D and Sumitran-Holgersson S: Isolation of precursor endothelial cells from peripheral blood for donor-specific crossmatching before organ transplantation. Transplantation 2002; Volume72, Number 11, 1479-1486
• Rodriguez P, Arroyave I, Mejia G, Garcia L: Detection of alloantibodies against non-HLA antigens in kidney transplantation by flow cytometry. Clinical Transplantation 2000; 14: 472-478
• Ball B, Mousson C, Ratignier F, Guignier D, Glotz D, Rifle G: Antibodies to vascular endothelial cells in chronic rejection of renal allografts. Transplantation Proceedings 2000; 32: 353-354
• Ferry B, Welsh K, Dunn M, Law D, Proctor J, Chapel H, Yacoub M, Rose M: Anti-cell surface endothelial antibodies in sera from cardiac and kidney transplant rejections: association with chronic rejection. Transplant Immunology 1997; 5: 17-24
• Sumitran-Karuppan S, Tydén G, Reinholt F, Berg U, Möller E: Hyperacute rejections of two consecutive renal allografts and early loss of the third transplant caused by non-HLA antibodies specific for endothelial cells. Transplant Immunology 1997; 5: 321-327

Publications on cross match testing

• Horsburgh T et al.: Crossmatching for renal transplantation- a 5 year review of different cytotoxic and flow cytometric methods showing importance of the IgG anti-B-lymphocyte FACS cross match. Transplantation Proceedings 1997; 29: 1458-1459