A Tool for enhanced risk assessment

The last decades there has been a substantial increase in short-term and long-term survival of transplanted grafts from both living and diseased donors (1). Nevertheless acute rejection affecting long-term graft survival remains a significant problem. Despite lymphocyte cross-matches, approximately 15-20% of kidneys undergo early rejections (2).

A multicenter study of XM-ONE®, an endothelial crossmatch test, demonstrated that XM-ONE® detects patients at risk of acute rejections (3).

1. Hariharan S et al, N Engl J Med 2000, 342:605-12. 2. Sumitran-Holgersson S and Holgersson J, Current Opinion in Organ Transplantation 2006, 11:425-432. 3. Breimer, M et al, Transplantation 2009, 87(4):549-556.

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AbSorber

AbSorber AB is a biotech company focused on developing products that increase the probability of transplantation success. XM-ONE®, the first AbSorber product on the market, is a CE-marked and FDA registered transplantation crossmatch test kit. In contrast to current crossmatch testing, XM-ONE® rapidly detects antibodies specific for endothelial-specific antigens as well as antibodies specific to major transplantation antigens. read more»

2010atc_icon.jpgHighlighted Meeting

 

American Transplant Congress

Date: May 1-5, 2010
Location: San Diego, California

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